Description
The Genesis System with Celselect Slides™ enables automatic and efficient capture of cells from various liquid biopsies as well as other samples types for enrichment and enumeration applications. The slides utilize 140,800 individual microchambers to capture cells between 8-30 µm.
Features and Benefits
• One System, Two Applications: Automated cell capture for enumeration or enrichment on the same system
• Capture Mechanism: Capture cells based on size
• Sample Processing: High capture efficiency without preprocessing
• Customization: Genesis Protocol Builder Software Tool enables optimization for different samples types or antibody stains
Celselect Slides Enumeration/Immunolabeling Workflow
Sample is prepared with fixing reagent and loaded on to the instrument. Cells are captured and immunolabeled automatically in the Celselect Slides microchambers while smaller components (<8 µm) flow through the slide to waste. The Celselect Slide is imaged on an automated microscope and files can be imported for reporting.
Add fixing reagent to sample and load sample on to the instrument. Sample and staining reagents are prepped according to predefined protocols
Genesis System automates capture and immunolabeling on Celselect Slides
Image Celselect Slides on an automated microscope
Import files from microscope to Rare Cell Analysis Software, confirm cells of interest, and generate report
Celselect Slides Enrichment Workflow
Sample is prepared with the dilution buffer and loaded on to the instrument. Cells are captured automatically in the Celselect Slides while smaller components (<8 µm) flow through the slide to waste. Cells are recovered in a single tube for downstream analysis.
Add dilution buffer to sample and load sample on to the instrument
Genesis System automates capture and recovery of cells
Cells can be characterized with methods such as sequencing (bulk or single-cell), digital PCR, FISH, flow cytometry, or cells cultured for further in vitro and in vivo analysis
For applications which require protocol optimization or creation of new protocols for custom reagents or antibody labeling, the Genesis Protocol Builder Software Tool enables adjustment of parameters such as reagent dispensing, pump pressures, and incubation settings. Building custom protocols is performed on your local computer.
Included Components
• Genesis System
• Genesis Instrument Accessory Kit
• Celselect Accessory Kit
Related Products
• ddSEQ Single-Cell Isolator
• ddPCR
