Bio-Rad, AHP3098, PRMT2 antibody

Rabbit anti Human PRMT2 antibody recognizes protein arginine N-methyltransferase 2. PRMT2 methylates arginyl residues in proteins such as STAT3, FBL, histone H4 and functions as a coactivator of androgen receptor (AR)-mediated and estrogen receptor (ER)-mediated transactivation ( Qi et al . 2002 , Meyer et al . 2007 ). PRMT2 may inhibit NF-kappa-B transcription and promote apoptosis involved in growth regulation ( Ganesh et al . 2006 ). In humans, the C-terminal domain of pol II (CTD) comprises 52 repeats of the consensus heptapeptide Tyr1/Ser2/Pro3/Thr4/Ser5/Pro6/Ser7 that is phosphorylated by several kinases during transcription ( Zaborowska et al . 2016 ).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.