Bio-Rad, AHP849, Defensin Beta 2 antibody

Name: Defensin Beta 2 antibody
Brand: Bio-Rad
SKU: AHP849

Size: 0.1 mg, Goat anti Human Defensin Beta 2

Catalog Number: AHP849

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Category

Polyclonal Antibodies

Pack Size0.1 mg

TagsProduct Types Polyclonal Antibody

Description

Goat anti Human Defensin beta 2 polyclonal antibody recognizes human Defensin beta-2 (BD-2), a ~4.3kDa cationic antimicrobial peptide , also known as Beta-defensin 4A or Skin-antimicrobial peptide 1 (SAP-1) expressed primarily by epithelial cells of the respiratory tract and skin, and an important component of the innate immune response against microbial infections. Expression of BD-2 is induced during inflammation in response to bacterial products and cytokines, and is initially expressed in a precursor form, which is cleaved to release the C-Terminal active portion of the protein which is secreted by the neutrophil and binds to bacterial membranes causing their disruption.

Storage Information
This product is shipped at ambient temperature.
Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Specifications

General

Target Species	Human
Product Form	Purified IgG - lyophilized
Preservative Stabilisers	None present
Immunogen	Recombinant human Defensin beta-2 ( PHP161 ).
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
Product Type	Polyclonal Antibody
Isotype	Polyclonal IgG
Specificity	Defensin Beta 2
Preparation	Antisera to human Defensin beta 2 were raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Approx. Protein Concentrations	IgG concentration 0.1 mg/ml after reconstitution
UniProt	O15263
Entrez Gene	DEFB4A
GO Terms	GO:0042742 defense response to bacterium
Synonyms	BD-2
RRID	AB_566948
Reconstitution	Reconstitute with 1.0ml distilled water Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. N.B. For functional studies do not add sodium azide

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