Bio-Rad, HCA207, Adalimumab antibody | AbD18754_hIgG1

Name: Adalimumab antibody | AbD18754_hIgG1
Brand: Bio-Rad
SKU: HCA207

Size: 0.1 mg, Human anti Adalimumab (Drug/Target Complex)

Catalog Number: HCA207

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Category

Monoclonal Antibodies

Pack Size0.1 mg

TagsProduct Types Monoclonal Antibody

Description

Human anti Adalimumab, clone AbD18754_hIgG1 , is an antibody that specifically recognizes the adalimumab monoclonal antibody while complexed with TNFα. As clone AbD18754_hIgG1 is a complex-specific antibody that recognizes adalimumab bound to its target, TNFα, it does not recognize either free adalimumab or unbound TNFα. Clone AbD18754_hIgG1 can be used in assays to measure adalimumab that has been captured via immobilized TNFα. It can also be used to measure adalimumab/TNFα and biosimilar products using bioanalytical assays. Adalimumab (branded as Humira ® ) is a fully human monoclonal antibody (IgG1/kappa) approved for the treatment of ankylosing spondylitis, Crohn’s disease, psoriasis and several forms of arthritis. The antibody is specific for TNFα, and acts by blocking the activation of TNF receptors by TNFα. This inactivation down-regulates the inflammatory reactions associated with autoimmune diseases. View a summary of all anti-adalimumab antibodies

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

Specifications

General

Product Form	Human IgG1 antibody selected from the HuCAL phage display library and expressed in a human cell line. This antibody is supplied as a liquid.
Preservative Stabilisers	0.09% Sodium Azide (NaN 3 )
Immunogen	Adalimumab/TNFα complex
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
Product Type	Monoclonal Antibody
Clone	AbD18754_hIgG1
Isotype	IgG1
Specificity	Adalimumab
Region	(DRUG/TARGET COMPLEX)
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution	Phosphate buffered saline.
Approx. Protein Concentrations	Antibody concentration 0.5 mg/ml
Source	HKB-11
Synonyms	HUMIRA ®
Affinity	The intrinsic affinity of the monovalent form of this antibody is K D =67 nM as measured by real time, label-free molecular interaction analysis on immobilized Adalimumab/TNFα.

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