Bio-Rad, MCA489, Adenovirus antibody | B025 (AD51)

Mouse anti adenovirus antibody, clone B025 (AD51) recognizes all human adenoviruses serotypes. The most common infections caused by adenovirus are respiratory tract infections but some infections may also lead to conjunctivitis, skin-rash, diarrhea and bladder infections. Infant and children are most commonly affected by adenoviruses. Adenoviruses are icosahedral non-enveloped linear double-stranded DNA viruses. There are at least 51 serotypes, which are categorized into 6 species (A-F) based on molecular criteria. The virus capsid is composed of three different proteins: 12 fiber attachment proteins associated with 12 penton base proteins and 240 hexon proteins, which form the main capsid component ( Ebner et al. 2005 ). Mouse anti adenovirus antibody, clone B025 (AD51) reacts with the adenovirus specific hexon polypeptide. Due to their infectivity to both quiescent and proliferating cells, adenoviruses have also been used as vectors in vaccination and in gene therapy ( Thomas et al. 2002 and Abad et al. 2002 ).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.