CST, 3350S, ApoA1 (5F4) Mouse Monoclonal Antibody

Product Usage Information
Western Blotting: 1:1000
Storage
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.
Protocol
Available protocols: Western Blotting
Specificity / Sensitivity
ApoA1 (5F4) Mouse Monoclonal Antibody detects endogenous level of total ApoA1 protein.
Species Reactivity: Human
Source / Purification
Monoclonal antibody is produced by immunizing animals with a full-length recombinant human ApoA1.
Background
ApoAI (Apolipoprotein A1) is a major component of high density lipoprotein (HDL, the "good cholesterol") in plasma. It is produced in the liver and small intestine. ApoA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) that is responsible for the formation of plasma cholesteryl esters and promotes cholesterol efflux from tissues to the liver for excretion. Defects in ApoA1 are associated with high density lipoprotein deficiency (HDLD) and systemic non-neuropathic amyloidosis (1-3).
Alternate Names
Apo-AI; apo(a); ApoA-I; APOA1; Apolipoprotein A-I; Apolipoprotein A-I(1-242); Apolipoprotein A1; epididymis secretory sperm binding protein; HPALP2; MGC117399; ProapoA-I; Proapolipoprotein A-I; Truncated apolipoprotein A-I