Description
Product Usage Information
Western Blotting: 1:1000
Storage
Supplied in 140 mM NaCl, 3 mM KCI, 10 mM sodium phosphate (pH 7.4) dibasic, 2 mM potassium phosphate monobasic, 2 mg/mL BSA, and 50% glycerol. Store at -20°C. Do not aliquot the antibody.
Protocol
Available protocols: Western Blotting
Specificity / Sensitivity
alpha-Synuclein (D37A6) Rabbit Monoclonal Antibody (Biotinylated) detects endogenous levels of the α isoform of synuclein.
Species Reactivity: Mouse, Rat
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide surrounding Glu105 of mouse α-synuclein protein.
Background
α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinson's disease (1).
Alternate Names
alp; alpha SYN; alpha-Syn; Alpha-synuclein; alphaSYN; NACP; Non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; Snca; Syn; synuclein, alpha; SYUA
