Cytiva, 17544010, MacroCap SP, 25 mL

Name: MacroCap SP, 25 mL
Brand: Cytiva
SKU: 17544010

Catalog Number: 17544010

Pricing

Send an RFQ.

View RFQ List

Category

Process-Scale Chromatography Resins

Pack Size25 mL

TagsChromatography resins Ion exchange resins Chromatography products resin

CollectionsCytiva Chromatography Columns, Resins & Lab Glassware Cytiva Protein Analysis Equipment & Supplies Collection

Description

MacroCap SP is a cation exchanger designed for the purification of large biomolecules such as polyethylene glycol (PEG)-modified proteins (i.e., PEGylated proteins) that are intended for use as biopharmaceuticals.
Strong cation exchanger for PEGylated proteins and other large biomolecules.
High purity and yield of PEGylated proteins at high sample loads.
Highly porous base matrix makes extensive surface area available for adsorption of large molecules.
MacroCap SP is a cation exchanger designed to separate PEGylated proteins and other large biomolecules. It allows separation of mono- from oligo- and non-PEGylated proteins with high selectivity under high load conditions. MacroCap SP is based on acrylamide-dextran copolymer resins with mass transfer properties suitable for large biomolecules. The base matrix is highly porous, which gives high available surface area for adsorption of PEGylated proteins. The large pore size also makes MacroCap SP suitable for binding other large proteins, e.g. IgM.
MacroCap SP is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, MacroCap SP meets industrial demands with security of supply and comprehensive technical and regulatory support.

Specifications

General

Chromatography technique	Ion Exchange Chromatography
BioProcess resin	Yes
Chemical stability	Commonly used aqueous buffers, 0.5 M NaOH, 0.1 M citric acid, 25% ethanol, 30% propanol, 30% methanol, 50% ethylene glycol, 1% Tween-20, and 1% SDS.
Flow rate	< 120 cm/h in BPG 300, 20-cm bed height or 70 cm/h in BPG 300, 30-cm bed height using process buffers with the same viscosity as water at v 3 bar (0.3 MPa)
Ion Exchanger Type	Strong cation exchanger
Ionic Capacity	0.10-0.13 mmol H + /ml medium
Ligand	SO3-
Matrix	Acrylamide-dextran copolymer
Particle size, d 50V	~50 µm
Storage	4 to 30°C 0.2 M Sodium Acetate in 20% Ethanol
pH stability, CIP	2–13
pH stability, operational	4–11

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.