Cytiva, 17544802, Capto Blue, 500 mL

Capto Blue affinity resin with Cibacron Blue ligand has outstanding pressure and flow properties, allowing rapid processing of large sample volumes of albumin and other proteins.
Excellent chemical stability ensures tolerance of harsh solvents used in repeated cleaning-in-place and sanitization procedures.
Capto Blue can be autoclaved repeatedly.
Highly rigid agarose base matrix allows high flow rates and processing of large sample volumes with no reduction in binding capacity.
Ligand functionality can be modified through the use of appropriate buffer salts and buffer conductivity to increase selectivity for desired targets.
Excellent choice for the removal or purification of proteins at both laboratory and process scales.
Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.
Capto Blue applications
Uses of Capto Blue and Capto Blue (high sub):
capture of human serum albumin (HSA)
purification of HSA fusion proteins
purification of blood coagulation factors, enzymes, and recombinant proteins
Improvements compared with predecessor resin
Developed from Blue Sepharose 6 Fast Flow, Capto Blue products are more chemically stable and have a more rigid agarose base matrix than their predecessor. These improvements allow the use of higher flow rates and larger sample volumes, enabling increased throughput and improved process economy.
Prepacked columns and other formats
Capto Blue is available in the following formats:
Process development scale – prepacked
HiScreen Capto Blue columns – optimized for method and process development.