Description
Protein L chromatography column HiTrap™ Protein L column is packed with Capto™ L resin . This resin combines a rigid, high-flow agarose matrix with the immunoglobulin-binding recombinant protein L ligand, which has a strong affinity to the variable region of antibody kappa light chains. The high binding capacity and affinity to a broad range of antibody fragments makes this resin an excellent capture platform for antibody fragments containing kappa light chains. Common uses include domain antibody, scFv, and Fab purification. Successful use in published research HiTrap™ Protein L is used in a variety of research applications, including: Characterization of a human colorectal cancer MDR1/P-gp Fab Purification optimization of an scFv against type 1 insulin-like growth factor receptor (IGF-1R) Other Cytiva Capto™ L chromatography columns and formats Capto™ L resin is also available in the following formats: Bulk Capto™ L resin HiScreen Capto™ L prepacked column, for method and process development PreDictor Capto™ L 96-well plate for high-throughput screening or process development.