Description
The small column volume of 4.7 mL and bed height of 10 cm make HiScreen™ columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, since the 10 cm bed height gives enough residence time and the results can then serve as basis for linear process scale-up. If necessary, two columns can easily be connected in series to give a bed height of 20 cm. Resins prepacked in HiScreen Capto™ IEX columns are also available in other formats and as bulk packs, which makes it possible to use the same resins for development work, pilot studies, and routine production.