Description
Overview
The Infinium Asian Screening Array Kit contains 24-sample BeadChips plus reagents for population genetic studies in East and Southeast Asian populations.
Uses an East Asian reference panel containing > 9K whole-genome sequences, including coverage of populations underrepresented in the 1000 Genomes Project
Includes updated clinical research and disease-related content
Maintains high data quality with > 99% call rates and > 99.9% reproducibility
Expert selected content
This microarray was designed in collaboration with leading institutions. Content includes a genome-wide backbone using clinical research variants, QC markers, a discovery panel, and custom add-on content.
Widely adopted
This microarray builds on the commercial success of the Infinium Global Screening Array. > 20M samples of Illumina Infinium arrays have been ordered by a global community of users.
Robust and scalable
Genotyping and CNV calling are supported for multiple sample types (eg, saliva, blood, buccal swabs, and FFPE samples). The high-throughput workflow maximizes sample processing while minimizing costs, instrumentation, lab space, and hands-on time.
Predesigned booster content is available as an optional add-on.
Applications
The Infinium Asian Screening Array-24 v1.0 BeadChip enables cost-effective, scalable genomic screening of East Asian populations for a broad range of clinical research and variant screening applications, including disease association and risk profiling studies, pharmacogenomics research, disease characterization, lifestyle and wellness characterization, and marker discovery in complex disease.
Example workflow
Human genotyping
iScan System
Infinium Automation Option Packages
BaseSpace Clarity LIMS
GenomeStudio Software
Beeline Software
Related applications and methods
High-throughput genotyping
Large-scale genotyping with microarrays can identify variants associated with disease risk in large cohorts or populations.
Human genotyping
Human genotyping arrays are ideal for processing thousands of samples to identify variants associated with traits and disease.
Complex and genetic disease research
Comprehensive array and next-generation sequencing (NGS) solutions can accelerate research of various genetic complex diseases.
Bringing meaning to genetic information
Scalable high-throughput array enables ethnic Chinese genome database development
Clinical research content on the Infinium Asian Screening Array
Content was expertly selected from scientifically recognized databases to create a highly informative array for clinical research applications. Variant counts are current as of August 2018 and may be subject to change.
Broad spectrum of pharmacogenomics markers
Clinical research content features an extensive list of pharmacogenomics markers selected based on CPIC1 guidelines and the PharmGKB2 database. Markers are arranged according to level of evidence as defined by the PharmGKB database. VIP, very important pharmacogene.
Whole-genome sequences used to build the Infinium Asian Screening Array
Whole-genome sequencing data used to build the Infinium Asian Screening Array-24 v1.0 BeadChip include Korean, Mongolian, and Malaysian samples currently not represented in publicly available reference populations.
Population: Abbreviation
Chinese: CHS-GIS
Southern Han Chinese: CHS
Chinese Dai: CDX
Han Chinese: CBD
Japanese: R-JAP1
Japanese: R-JAP2
Japanese: R-JAP3
Japanese: K-JAP
Japanese: JAP
Korean: M-KOR
Korean: KPGP
Malaysian: MAL
Mongolian: MON
Vietnamese: KVT
Clinical Pharmacogenetics Implementation Consortium (CPIC). cpicpgx.org . Accessed October 2016.
PharmGKB, The Pharmacogenomics Knowledgebase. www.pharmgkb.org . Accessed January 2017.
Infinium Asian Screening Array-24 v1.0 Kit (48 samples)
20016317
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 2 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples. View less
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Infinium Asian Screening Array-24 v1.0 Kit (288 samples)
20016318
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 12 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 288 DNA samples. View less
Infinium Asian Screening Array-24 v1.0 Kit (1152 samples)
20016319
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 1152 DNA samples. View less
Infinium™ Asian Screening Array-24+ v1.0 Kit (48 samples)
20016320
Infinium™ Asian Screening Array-24+ v1.0 Kit (288 samples)
20016321
Infinium™ Asian Screening Array-24+ v1.0 Kit (1152 samples)
20016322
Infinium FFPE QC Kit (384 reactions)
WG-321-1001
Infinium FFPE QC Kit is an accessory product required to qualify FFPE samples with Nextera Flex for Enrichment. Library prep, enrichment, enrichment probe panel, and index adapter reagents need to be ordered separately. View less
Infinium HD FFPE DNA Restore Kit (24 samples)
WG-321-1002
Contains a combination of novel reagents that are used to restore damaged FFPE DNA. Restored DNA can be genotyped using Illumina FFPE enabled Infinium BeadChips to achieve quality data. The Infinium FFPE Restore Kit is supplied with enough reagents to restore 24 FFPE DNA samples. View less
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