Description
Overview
The Illumina and GenoScreen Deeplex® Myc-TB Combo Kit is a targeted next-generation sequencing panel for the identification of Mycobacterium tuberculosis complex (MTBC) strains, mycobacterial species identification, genotyping, and prediction of drug resistance mutations of MTBC strains. Data analysis is included via a cloud-based Deeplex® software web application with results visualization. Two kit options are available based on which library prep is desired.
Identification of resistance mutations to 15 anti-tuberculosis drugs
Genotyping and spoligotyping of MTBC strains to determine lineage and sublineage of strains present in a sample
Identification of >140 mycobacterial species and detection of co-infections with distinct species
Total turnaround time less than 48 hours directly from sputum with no need to perform culture
Combo kits contain either Illumina DNA Prep (IDP) or Nextera XT library prep, plus the Deeplex® Myc-TB multiplex panel, indexes, and bioinformatic analysis. Choose the SKU that includes the library prep you prefer.
Example workflow
Illumina and GenoScreen Deeplex® Myc-TB Combo Kit
iSeq 100 System
MiniSeq System
MiSeq System
NextSeq 550 System
Related applications and methods
Tuberculosis sequencing
Next-generation sequencing is advancing the detection, characterization, and surveillance of drug-resistant tuberculosis strains.
Antimicrobial resistance detection
Next-generation sequencing offers high-throughput capabilities to identify genomic changes associated with antimicrobial resistance.
Public health surveillance
Genomics can advance public health and wellness by detecting and characterizing new, emerging, and circulating pathogens.