Illumina, HDA-HS-1012-24, OncoReveal Nexus 21 Gene Panel

Name: OncoReveal Nexus 21 Gene Panel
Brand: Illumina
SKU: HDA-HS-1012-24

OncoReveal Nexus 21 Gene Panel

Catalog Number: HDA-HS-1012-24

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Category

NGS Library Preparation Kits

TagsSequencing kits Library preparation kits

Description

Overview
The oncoReveal Nexus 21 Gene Panel is a robust NGS research assay designed to interrogate 21 genes relevant to both blood cancers and solid organ cancers. The panel uses proprietary Stem-Loop Inhibition-Mediated amplification (SLIMamp) technology, a tiled amplicon-based library prep chemistry, for efficient single-tube target enrichment.

Key features
Access a rapid workflow to go from sample to report in < 24 hours
Achieve variant detection as low as 1% VAF even with limited DNA input or poor sample quality
Improve lab efficiency and reduce "no calls," and repeat testing to simplify data interpretation
The panel detects single nucleotide variants (SNVs), small and medium insertion/deletions (indels), and internal tandem duplicates (ITDs) in DNA isolated from blood or FFPE tissue.
This panel uses a streamlined enrichment workflow for fast preparation of sequencing libraries, helping labs move from extracted DNA to data generation within the same day.
Maintain control of samples and results with single-tube, tiled amplification that can be performed in-house by any NGS lab.

Applications
The Pillar oncoReveal Nexus 21 Gene Panel analyzes DNA extracted from solid tumors or blood cancers in under 8 hours of sample processing time with just 3 hours of hands-on time.

Example workflow
Pillar oncoReveal Nexus 21 Gene Panel
MiSeq i100 Series
MiSeqDx Instrument (RUO mode)
DRAGEN Amplicon
Illumina Connected Insights

Figures
Gene list
Pillar oncoReveal Nexus 21 Gene Panel includes 21 genes
Panel specifications
Pillar oncoReveal Nexus 21 Gene Panel specifications for interrogating DNA from FFPE tissue or blood
OncoReveal Nexus 21 Gene Panel
HDA-HS-1012-24
OncoReveal Nexus 21 Gene Panel View less
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Specifications

General

Assay time	< 8 hrs assay time; < 24 hrs sample to result
Hands-on time	~3 hr
Input quantity	20–60 ng DNA
Content specifications	21 genes
Description	NGS assay that analyzes key mutations in 21 genes relevant to solid tumors and blood cancers.
Instruments	MiSeq System , MiSeqDx in Research Mode , MiSeq i100 Plus System , MiSeq i100 System
Mechanism of action	Multiplex PCR using tiled amplicon
Method	Targeted DNA sequencing , Amplicon sequencing
Nucleic acid type	DNA
Number of amplicons	Pool 1: 112 amplicons
Number of reactions	24 reactions per kit
On-target reads	> 99%
Specialized sample types	Blood, Low-input samples, FFPE tissue
Species category	Human
Target insert size	162 bp
Technology	Sequencing
Variant class	Single nucleotide variants (SNVs), Insertions-deletions (indels), Internal tandem duplications (ITDs)

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

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