Description
Overview
The oncoReveal Multi-Cancer with CNV and RNA Fusion Panel is a combined DNA/RNA multi-cancer panel. The assay combines the DNA-based oncoReveal Multi-Cancer v4 with CNV Panel with the oncoReveal Multi-Cancer RNA Fusion v2 Panel allowing for joint sequencing. The assay uses proprietary Stem Loop Inhibition-Mediated amplification (SLIMamp) technology, a tiled amplicon-based library prep chemistry for efficient single-tube target enrichment.
Maintain control of samples and results with single-tube, tiled amplification that can be performed in-house by any NGS lab
Achieve variant detection as low as 1% VAF without UIDs, even with limited DNA input or poor sample quality
Improve lab efficiency and reduce “no calls,” repeat testing and difficult interpretation decisions
In under 8 hours from DNA to sequencer and under 9–10 hours from RNA to sequencer
Example workflow
Pillar oncoReveal Multi-Cancer CNV + RNA Fusion Panel
MiSeq i100 Series
MiSeq System
NextSeq 550 System
Illumina Connected Insights
Gene list
Pillar oncoReveal Multi-Cancer CNV + RNA Fusion Panel interrogates variants across 60 genes from DNA and 18 driver genes from RNA.
Panel specifications
Pillar oncoReveal Multi-Cancer CNV + RNA Fusion Panel specifications for interrogation of DNA and RNA from tissue biopsy.
oncoReveal™ Multi-Cancer CNV + Fusion
HNA-HS-1001-48
oncoReveal™ Multi-Cancer CNV + Fusion View less
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Indices PI501-8, PI701-4 (32 combinations, 96 reactions)
IDX-PI-1001-96
Indices PI501-8, PI701-4 (32 combinations, 96 reactions) View less
Kit D, indices PI501-8, PI701-12
IDX-PI-1004-192
Kit D, indices PI501-8, PI701-12 View less
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