Illumina, HRA-HS-1002-24, oncoReveal™ MultiCancer RNA Fusion v2 Pnl 24rxn

Pillar oncoReveal Multi-Cancer RNA Fusion v2 Panel
Targeted panel targeting 83 RNA fusions from FFPE tissue across multiple solid tumor types.
Pillar oncoReveal MulticancerRNA Fusion v2 Panel Data sheet PDF < 1 MB
Data sheet PDF < 1 MB
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Overview
The Pillar oncoReveal Multi-Cancer RNA Fusion v2 Panel is a robust NGS assay designed to interrogate 18 driver genes and 83 fusion partners relevant across multiple solid tumor types using RNA isolated from formalin-fixed, paraffin-embedded (FFPE) samples.

Key features
Rely on a rapid workflow going from sample to report within 48 hours
Achieve sensitive and robust fusion detection without UIDs even with limited RNA input or poor sample quality
Improve lab efficiency and reduce “no calls”
This focused panel can detect gene rearrangements in RNA isolated from FFPE tissue.
The assay uses proprietary Stem-Loop Inhibition-Mediated amplification (SLIMamp) technology, a tiled amplicon-based library prep chemistry for efficient single-tube target enrichment.
The workflow allows labs to maintain control of samples and results with single-tube, tiled amplification that can be performed in-house by any NGS lab.

Applications
The Pillar oncoReveal Multi-Cancer RNA Fusion v2 Panel analyzes multiple solid tumor types using RNA isolated from FFPE samples in under 9 hours with approximately 3 hours of hands-on time.

Example workflow
Pillar oncoReveal Multi-Cancer RNA Fusion v2 Panel
MiSeq i100 Series
MiSeqDx Instrument (RUO mode)
NextSeq 550 System
NextSeq 550Dx Instrument (RUO mode)
Illumina Connected Insights

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Figures
Gene List
Pillar oncoReveal Multi-Cancer RNA Fusion v2 Panel includes 18 driver genes and 83 partners.
Panel Specifications
Pillar oncoReveal Multi-Cancer RNA Fusion v2 Panel specifications for interrogation of fusion transcripts (RNA) isolated from FFPE tissue.
oncoReveal™ MultiCancer RNA Fusion v2 Pnl 24rxn
HRA-HS-1002-24
18 gene (24 sample) solid tumor RNA panel on SLIMamp™ workflow View less
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