Description
General description
Interleukin 13 (IL-13) is secreted by a number of cells including T helper cells, CD4 cells and a various white blood cells and is thought to be a mediator of allergic inflammation in many tissues via the induction of IgE synthesis by B cells. Although primarily associated with the induction of airway disease, IL-13 has also been shown to inhibit the production of proinflammatory cytokines by monocytes and macrophages suggesting it has important anti-inflammatory properties.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
Unparalleled Sensitivity: The SMC®technology delivers exceptional performance in quantifying IL-13 in human serum and plasma, enabling precise measurements.
Enhanced Research Insights: The ability to detect low levels of IL-13 provides valuable insights into immune responses, inflammation, and disease mechanisms.
Cost-Effective: By allowing for the detection of low-abundance cytokines, these assays can reduce the need for larger sample volumes and repeated testing, ultimately saving time and resources.
Streamlined Laboratory Operations: The kit′s design and features enhance workflow efficiency, allowing researchers to focus on data generation rather than preparation.
Packaging
96 well assay
Analysis Note
Sensitivity: LLOQ 40 fg/mL* (SMCxPRO® Instrument)
Standard Curve Range: 20-100,000 fg/mL
Intra-assay CV: Inter-assay CV: Linearity: Serum: 95% Plasma: 100%
Recovery: Serum: 88% Plasma: 89%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
Although IL-13 was detectable in guinea pig, non-human primate, rat, rabbit and canine samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
