Merck, 03-0191-00, SMC® Human IFN-β1 High Sensitivity Immunoassay Kit

General description
A member of the type I interferon family of glycoprotein second messengers, human Interferon Beta (IFN-ß1) has been associated with antiviral activity as a secreted factor from infected cells that mediates innate immunity in neighboring cells. In addition, IFN-β1 has also been utilized as treatment for Multiple Sclerosis (MS) due to its ability to ameliorate inflammation in the central nervous system in this disease.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease / Neurodegenerative Diseases / Neurodegenerative Medicine / Virology / Infectious Diseases - Viral / Immunological Signaling
Features and Benefits
Reveal the First Responders of Immunity: IFN-β1 is a frontline cytokine in antiviral defense; this kit helps you detect its earliest signals.
Empower Neuro and Autoimmune Research: Quantify IFN-β1 in studies of multiple sclerosis, lupus, and other inflammatory conditions with confidence.
Precision You Can Count On: Built for reproducibility, with tight CVs across operators and days, because your data deserves consistency.
Molecular-Level Listening: Detects IFN-β1 at whisper-quiet levels, down to 150 fg/mL, thanks to ultrasensitive SMC® technology.

Packaging
96 well assay
Analysis Note
Sensitivity: LLOQ 150 fg/mL* (SMCxPRO® Instrument)
Standard Curve Range: 70-170,000 fg/mL
Intra-assay CV: Inter-assay CV: Linearity: Serum: 108% Plasma: 108%
Recovery: Serum 88% Plasma: 93%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
Assay Buffer
IFN-β1 Coated Beads
Standard Diluent
IFN-β1 Detection Antibody
IFN-β1 Standard
10X Wash Buffer
Buffer D
Elution Buffer B

Although IFNβ1 was detectable in non-human primate, rat, mouse, feline, and canine samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.