Merck, 1029002-200MG, Amitriptyline hydrochloride

Name: Amitriptyline hydrochloride
Brand: Merck
SKU: 1029002-200MG

Size:200 mg, United States Pharmacopeia (USP) Reference Standard

Catalog Number: 1029002-200MG

Pricing

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Category

pH Standards

Pack Size200 mg

TagsAnalytical Chemistry Reference Materials Pharma Standards

CollectionsMerck Certified Reference Materials: CRMs for Calibration, QC & Instrument Validation Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Amitriptyline hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
Amitriptyline Hydrochloride Tablets
Chlordiazepoxide and Amitriptyline Hydrochloride Tablets
Cyclobenzaprine Hydrochloride Extended-Release Capsules
Perphenazine and Amitriptyline Hydrochloride Tablets

Biochem/physiol Actions
Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.
Tricyclic antidepressant; norepinephrine and serotonin transporter inhibitor; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.

Specifications

General

NACRES	NA.24
PubChem Substance ID	329749005
UNSPSC Code	41116107
MDL number	MFCD00012537
InChI key	KFYRPLNVJVHZGT-UHFFFAOYSA-N
SMILES string	Cl[H].CN(C)CC\C=C1\c2ccccc2CCc3ccccc13
InChI	1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
grade	pharmaceutical primary standard
API family	amitriptyline
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
format	neat
Gene Information	human ... SLC6A2(6530), SLC6A4(6532)

Ordering

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