Merck, 13024AST, Astec® CHIROBIOTIC® R Chiral HPLC Column

Name: Astec® CHIROBIOTIC® R Chiral HPLC Column
Brand: Merck
SKU: 13024AST

Size:1 ea, Chiral Recognition HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

Catalog Number: 13024AST

Pricing

Send an RFQ.

View RFQ List

Category

Chiral HPLC Columns

Pack Size1 ea

TagsHPLC Columns Analytical Chemistry Analytical Chromatography

CollectionsMerck Analytical Chromatography Products & Lab Supplies Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
CHIROBIOTIC® R, based on the ristocetin A glycopeptide covalently bonded to high purity silica particles, has shown particular applicability to enantiomers of anionic compounds. Selectivity on CHIROBIOTIC® R strongly correlates to the organic modifier, favoring the alcohol-type mobile phases by a large margin.

Bonded phase: Ristocetin A
Operating pH range: 3.5 - 6.8
Particle diameter: 5, 10 or 16 μm
Pore size: 100 Å

CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature
Application

Sensitive Determination of Lactic Acid Isomers: The Astec® CHIROBIOTIC® R Chiral HPLC Column was crucial in a study by Henry H et al., where it facilitated the sensitive determination of D-lactic acid and L-lactic acid in urine using high-performance liquid chromatography-tandem mass spectrometry. This method is pivotal for clinical diagnostic applications, showcasing the column′s ability to resolve similar compounds that are challenging to differentiate by other means (Henry H et al., 2012).

Enantioseparation of Cyclopentanecarboxylic and Cyclohexanecarboxylic Acids: The column was also utilized by Berkecz R et al. to achieve high-performance liquid chromatographic enantioseparation of complex 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids. This application underscores the column′s versatility and efficacy in separating closely related chiral acids, essential for biochemical research and pharmaceutical product development (Berkecz R et al., 2009).

Other Notes
Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

Specifications

General

UNSPSC Code	41115700
eCl@ss	32110501
Web Name Suffix Override	L × I.D. 25 cm × 4.6 mm, HPLC Column
Web Name Override	Astec® CHIROBIOTIC® R Chiral (5 μm) HPLC Columns
NACRES	SB.52
material	stainless steel column
description	HPLC column
product line	Astec®
packaging	pkg of 1 ea
manufacturer/tradename	Astec®
parameter	0-45 °C temperature
technique(s)	HPLC: suitable
L × I.D.	25 cm × 4.6 mm
matrix	high-purity silica gel particle platform
matrix active group	ristocetin A glycopeptide phase
particle size	5 μm
pore size	100 Å
operating pH range	3.5-6.8
separation technique	chiral
Quality Level	100

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.