Merck, 14-909-M, MELK Protein, active, 0 0

General description
Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
Product Source: Recombinant protein of the human MELK gene expressed by baculovirus in insect cells
Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag
Application
Research Category
Signaling
Biochem/physiol Actions
Target Sub-Family: CAMK
Packaging
Also available in 250μg size - call for pricing and availability and reference catalog number 14-909M when ordering the 250μg size
Physical form
Purified using glutathione-agarose
Preparation Note
6 months at -70°C
Analysis Note
Routinely evaluated by phosphorylation of KKLNRTLSFAEPG
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.