Merck, 580560-1GM, TCEP, Hydrochloride

Name: TCEP, Hydrochloride
Brand: Merck
SKU: 580560-1GM

Size:1 g, TCEP, Hydrochloride, tris(2-Carboxyethyl)phosphine, HCl, A water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT.

Catalog Number: 580560-1GM

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Category

Chelating Agents

TagsChemistry & Biochemicals Biochemicals Chelating & Reducing Agents

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
A water-soluble and odorless disulfide reducing agent which is more stable and effective than DTT. TCEP reduces even the most stable water-soluble alkyl disulfides at pH 4.5 within 5 min. TCEP is also capable of functioning as a reducing agent even in pH range of 1.5-8.5. Is more resistant to air-oxidation as compared to DTT.
Application

Peptide and Protein Desulfurization with Diboron Reagents.: This study investigates the use of TCEP hydrochloride in peptide and protein desulfurization, demonstrating its effectiveness in facilitating diboron-mediated reactions. (Jing & Walczak, 2024).

A Study on Thiol-Michael Addition to Semi-Synthetic Elastin-Hyaluronan Material for Electrospun Scaffolds.: TCEP hydrochloride is utilized to enhance the thiol-Michael addition reaction in the development of electrospun scaffolds, contributing to advanced biomaterials research. (Laezza et al., 2024).

Optimized total RNA isolation from bovine sperm with enhanced sperm head lysis.: This paper presents an optimized protocol for RNA isolation from bovine sperm, highlighting the role of TCEP hydrochloride in improving sperm head lysis efficiency. (Tiwari et al., 2024).

Target Recognition-Triggered Peroxidase-Mimicking Activity Depression in Homochiral Nanochannels for Identifying Cystine Enantiomers.: The study uses TCEP hydrochloride in a novel peroxidase-mimicking system to differentiate cystine enantiomers, showcasing its application in chiral analysis. (Xu et al., 2023).

In situ digestion of alcohol-fixed cells for quantitative proteomics.: TCEP hydrochloride is applied in the in situ digestion of fixed cells to enhance the accuracy of quantitative proteomics analyses. (Hatano et al., 2023).

Packaging
Packaged under inert gas
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Corrosive (L)

Specifications

General

UNSPSC Code	12352128
NACRES	NA.25
MDL number	MFCD00145469
SMILES string	P(CCC(=O)[O-])(CCC(=O)[O-])CCC(=O)[O-]
InChI	1S/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)/p-3
InChI key	PZBFGYYEXUXCOF-UHFFFAOYSA-K
assay	≥98% (elemental analysis)
form	crystalline solid
reaction suitability	reagent type: reductant
manufacturer/tradename	Calbiochem®
storage condition	OK to freeze
color	white
solubility	water: 5 mg/mL
shipped in	ambient
storage temp.	2-8°C
Quality Level	100

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