Merck, 667005-1G, (R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane

Name: (R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane
Brand: Merck
SKU: 667005-1G

Size:1 g, (R)-(+)-2-(Trifluoromethyl)oxirane, 97%

Catalog Number: 667005-1G

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Category

Heterogeneous Catalysts

Pack Size1 g

TagsCatalysts Chemistry & Biochemicals Chiral Catalysts & Ligands

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Application
(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize:
Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
(2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.

Specifications

General

NACRES	NA.22
PubChem Substance ID	24884878
UNSPSC Code	12352005
MDL number	MFCD08276876
InChI	1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2/t2-/m1/s1
SMILES string	FC(F)(F)[C@H]1CO1
InChI key	AQZRARFZZMGLHL-UWTATZPHSA-N
assay	97%
refractive index	n20/D <1.300
bp	25-32 °C
density	1.294 g/mL at 25 °C
functional group	ether
storage temp.	2-8°C
Quality Level	100

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