Merck, 700052P-1MG, 22(R)-hydroxycholesterol-d7

Name: 22(R)-hydroxycholesterol-d7
Brand: Merck
SKU: 700052P-1MG

Size:1 mg, 25, 26, 26, 26, 27, 27, 27-heptadeuterocholest-5-ene-3β, 22R-diol, Avanti Research™ - A Croda Brand

Catalog Number: 700052P-1MG

Pricing

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Category

Dry Ice

Pack Size1 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol. It is present in the neonate brain. 22(R)-hydroxycholesterol-d7 is a deuterated form of 22(R)-hydroxycholesterol.
Biochem/physiol Actions
22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimer′s disease and may be implicated in neuroinflammation and neurodegenerative diseases.
Packaging
5 mL Amber Glass Screw Cap Vial (700052P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD00272990
NACRES	NA.25
UNSPSC Code	41141804
description	cholest-5-ene-3β,22(R)-diol-d7
assay	>99% (TLC)
form	powder
packaging	pkg of 1 × 1 mg (700052P-1mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand
application(s)	lipidomicsmetabolomics
shipped in	dry ice
storage temp.	−20°C

Ordering

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