Merck, 700136P-1MG, 7α,27-dihydroxycholesterol-d6

Name: 7α,27-dihydroxycholesterol-d6
Brand: Merck
SKU: 700136P-1MG

Size:1 mg, 7α, 27-dihydroxycholesterol-d6, Avanti Research™ - A Croda Brand 700136P, powder

Catalog Number: 700136P-1MG

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Category

Dry Ice

Pack Size1 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
7α,27-dihydroxycholesterol (7α,27-di-OHC) is synthesized by the hydroxylation of 27-hydroxycholesterol (27-OHC). It is an oxysterol with side chains oxidized and is a structural isomer of 7α,25-dihydroxycholesterol. 7α,27-dihydroxycholesterol-d6 is a deuterated derivative of 7α,27-di-OHC.
Application
7α,27-dihydroxycholesterol-d6 has been used as a deuterated internal standard in liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS) for human plasma oxysterol analysis.
Biochem/physiol Actions
7α,27-dihydroxycholesterol (7α,27-di-OHC) is a ligand for Epstein-Barr virus-induced gene 2 (EBI2). 7α27-di-OHC is implicated in neurological disease, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human cerebrospinal fluid (CSF) samples. The levels of 7α,27-di-OHC decreases in lipopolysaccharide activation.
Packaging
5 mL Amber Glass Screw Cap Vial (700136P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD00152125
Web Name Suffix Override	Avanti Research™ - A Croda Brand
NACRES	NA.25
UNSPSC Code	12352211
assay	>99% (TLC)
form	powder
packaging	pkg of 1 × 1 mg (700136P-1mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 700136P
shipped in	dry ice
storage temp.	−20°C

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