Merck, 700138P-1MG, 7-dehydrodesmosterol

Name: 7-dehydrodesmosterol
Brand: Merck
SKU: 700138P-1MG

Size:1 mg, Cholesta-5, 7, 24-trien-3β-ol, powder

Catalog Number: 700138P-1MG

Pricing

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Category

Dry Ice

Pack Size1 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
7-dehydrodesmosterol (7-DHD) is synthesized via the Bloch pathway. 7-DHD serves as a desmosterol synthesis precursor and the enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes this step.
Application
7-dehydrodesmosterol has been used as an internal oxysterol standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
Biochem/physiol Actions
7-dehydrodesmosterol (7-DHD) levels are higher during fetal development and increases with aging. Elevated levels of 7-DHD is associated with Smith-Lemli-Opitz syndrome mouse model. Reduced levels of 7-DHD is observed in shiverer and quaking disorder.
Packaging
5 mL Amber Glass Screw Cap Vial (700138P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD28359052
UNSPSC Code	12352211
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
SMILES string	O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@@H](CC[C@@H]4[C@@H](CCC=C(C)C)C)C3=CC=C2C1)C)C
InChI	1S/C27H42O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9-10,19,21,23-25,28H,6,8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1
InChI key	RUSSPKPUXDSHNC-DDPQNLDTSA-N
assay	>99% (TLC)
form	powder
packaging	pkg of 1 × 1 mg (700138P-1mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 700138P
shipped in	dry ice
storage temp.	−70°C

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