Merck, 710332C-25MG, 14:0 Cardiolipin (ammonium salt)

Name: 14:0 Cardiolipin (ammonium salt)
Brand: Merck
SKU: 710332C-25MG

Size:25 mg, 1, 1′, 2, 2′-tetramyristoyl cardiolipin (ammonium salt); 1, 1′, 2, 2′-tetratetradecanoyl cardiolipin (ammonium salt); CL(1′-[14:0/14:0], 3′-[14:0/14:0]), 1′, 3′-bis[1, 2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt), chloroform

Catalog Number: 710332C-25MG

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Category

Dry Ice

Pack Size25 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
14:0 Cardiolipin is an acidic phospholipid. Structurally, cardiolipin comprises three glycerol moieties and four acyl chains and is localized in the inner membrane of mitochondria. 14:0 Cardiolipin contains four myristic acid as acyl chain.
Application
14:0 Cardiolipin (1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt)) has been used:
as a standard in tandem mass spectrometry
in the preparation of membrane proximal region (MPR) of human immunodeficiency virus (HIV-1) glycoprotein 41 (gp41)-lipopeptide conjugate and liposomes
as a component of micelle for suspending C8 ceramide substrate in ceramide kinase assay

Biochem/physiol Actions
Cardiolipin (CL) plays a key role in oxidative phosphorylation. CL is essential for energy production and in the activation of apoptosis. Deficiency of CL is associated with the development of diabetes and age-related heart failure. Anomalies associated with CL composition is observed in Barth Syndrome (BTHS).
Packaging
5 mL Clear Glass Sealed Ampule (710332C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD28359035
Web Name Suffix Override	Avanti Research™ - A Croda Brand
NACRES	NA.25
UNSPSC Code	51191904
assay	>99% (TLC)
form	solution
packaging	pkg of 1 × 2.5 mL (710332C-25mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 710332C
concentration	10 mg/mL (710332C-25mg)
lipid type	phospholipidscardiolipins
shipped in	dry ice
storage temp.	−20°C

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