Merck, 790528P-5MG, 18:1 DGS-NTA

General description
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (18:1 DGS-NTA) is amphiphile. DGS-NTA is a nitrilotriacetic acid -functionalized amphiphile devoid of nickel ion.
Application
18:1 DGS-NTA 1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (ammonium salt) has been used:
for generation of amphiphile monolayer
in NTA-liposome preparation for procoagulant binding studies and to study its effect on factor FXII autoactivation
as a liposome component for lipid bilayer preparation for surface plasmon resonance studies

Biochem/physiol Actions
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (18:1 DGS-NTA or DOGS-NTA) cannot bind to histidine due to lack of nickel ion. It is capable of self-assembly to form a stable monolayer. DOGS-NTA ammonium salt is useful in bicelle preparation.
Packaging
5 mL Clear Glass Sealed Ampule (790528P-5mg)
Legal Information
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