Merck, 791638C-1MG, 15:0-18:1-d7-PE

General description
15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) is a deuterated phospholipid. The lipid comprises phosphatidylethanolamine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylethanolamine is a membrane phospholipid and serves as an intermediate in other glycerophospholipid synthesis.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
Application
15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) has been used:
as a component of extraction solvent for lipid isolation from biological samples,
as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)
as an internal standard to spike plasma samples for fourier transform mass spectrometry (FTMS) analysis

Biochem/physiol Actions
Phosphatidylethanolamine (PE) regulates protein folding, protein modification, autophagy and cell division. PE serves as a substrate for glycosylphosphatidylinositol anchored proteins (GPI-APs) synthesis. Low levels of PE may be observed in Parkinson′s disease and may also inhibit protein maturation.
Packaging
2 mL Amber Glass Sealed Ampule (791638C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC