Merck, 808865-0.5ML, Gold nanoparticles

Name: Gold nanoparticles
Brand: Merck
SKU: 808865-0.5ML

Size:0.5 mL, Biotin Gold, 40 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H₂O

Catalog Number: 808865-0.5ML

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Category

Gold Nanoparticles

Pack Size0.5 mL

TagsMaterials Science Electronic Materials Inorganic & Metallic Nanomaterials

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Gold nanoparticles PEG 5000 biotin terminated.The preparation of biotinylated gold nanoparticles involves two surface modification steps. First the carboxyl-terminated alkanethiol is attached to the surface of gold nanoparticles via chemisorption in the presence of a stabilizing agent. This step is followed by the reaction of the carboxyl groups with (+)-biotinyl-3,6,9,-trioxaundecanediamine and 2-(2-aminoethoxy)ethanol.
Application
Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent and ranges from 515-520nm for a 5nm particle to 572nm for a 100nm particle.
Gold nanoparticles 40 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H₂O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.
Legal Information
Product of CytoDiagnostics, Inc.

Specifications

General

UNSPSC Code	12141717
NACRES	NA.23
InChI	1S/Au
InChI key	PCHJSUWPFVWCPO-UHFFFAOYSA-N
material	PEG 5000
form	dispersion in H2O
composition	, 3.58E12 particles/mL
packaging	pkg of 0.5 mL
storage condition	do not freeze
concentration	2.33 mg/mL in H2O
OD	50
surface area	7.74 m2/g
diameter	40 nm
pH	5-7
density	1.00 g/cm3
peak SPR wavelength	530 nm
functional group	biotin
storage temp.	2-8°C
Quality Level	100

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