Merck, 857324P-1MG, 17:0 Cyclic LPA

Name: 17:0 Cyclic LPA
Brand: Merck
SKU: 857324P-1MG

Size:1 mg, 1-heptadecanoyl-glycero-2, 3-cyclic-phosphate (ammonium salt), Avanti Research™ - A Croda Brand 857324P, powder

Catalog Number: 857324P-1MG

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Category

Dry Ice

Pack Size1 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate.
Application
17:0 Cyclic LPA or 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt) has been used as an internal standard for the quantification of cyclic lysophosphatidic acid (LPA) esters in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS).
Biochem/physiol Actions
cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.
Packaging
5 mL Amber Glass Screw Cap Vial (857324P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

UNSPSC Code	51191904
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
InChI	1S/C20H39O6P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(21)24-17-19-18-25-27(22,23)26-19;/h19H,2-18H2,1H3,(H,22,23);1H3/t19-;/m1./s1
InChI key	QQOXNBRKDUFLHW-FSRHSHDFSA-N
SMILES string	O=P1([O-])O[C@H](COC(CCCCCCCCCCCCCCCC)=O)CO1.[NH4+]
assay	>99% (TLC)
form	powder
packaging	pkg of 1 × 1 mg (857324P-1mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 857324P
lipid type	phospholipidscardiolipins
shipped in	dry ice
storage temp.	−20°C

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