Merck, 860817P-5MG, 17:0(2R-OH) Ceramide

Name: 17:0(2R-OH) Ceramide
Brand: Merck
SKU: 860817P-5MG

Size:5 mg, N-(2′-(R)-hydroxyheptadecanoyl)-D-erythro-sphingosine, Avanti Research™ - A Croda Brand 860817P, powder

Catalog Number: 860817P-5MG

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Category

Dry Ice

Pack Size5 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
17:0(2R-OH) Ceramide is a 2R hydroxylated heptadecanoic acid-containing sphingolipid. It is present mainly in epidermis.
Biochem/physiol Actions
Hydroxy fatty acids (hFA)-sphingolipids play a vital role in cell signaling. They also help in cell differentiation and apoptosis. hFA-ceramides are involved in the formation of the epidermal barrier. Fatty acid 2-hydroxylases (FA2H) synthesize hFA-ceramides. Mutations of FA2H have been linked to neurological disorders like spastic paraparesis in humans and leukodystrophy. hFA-ceramides in the cell membrane play a crucial role in imparting the PM02734 drug with anti-tumor activity.
Packaging
5 mL Amber Glass Screw Cap Vial (860817P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD22416673
UNSPSC Code	12352211
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
InChI	1S/C35H69NO4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(38)32(31-37)36-35(40)34(39)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-34,37-39H,3-26,28,30-31H2,1-2H3,(H,36,40)/b29-27+/t32-,33+,34+/m0/s1
InChI key	MBKBHFOACJJHAN-NBVWUYLUSA-N
SMILES string	CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCC)=O)CO
assay	>99% (TLC)
form	powder
packaging	pkg of 1 × 5 mg (860817P-5mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 860817P
lipid type	sphingolipids
shipped in	dry ice
storage temp.	−20°C

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