Merck, 870729P-5MG, 25:0 Coenzyme A

Name: 25:0 Coenzyme A
Brand: Merck
SKU: 870729P-5MG

Size:5 mg, pentacosanoyl Coenzyme A (ammonium salt), Avanti Research™ - A Croda Brand 870729P, powder

Catalog Number: 870729P-5MG

Pricing

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Category

Dry Ice

Pack Size5 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
25:0 Coenzyme A or pentacosanoyl coenzyme A is a long chain fatty acyl-CoA. Fatty acyl-CoAs is produced from de-novo fatty acid biosynthesis and the reprocessing of pre-existing fatty acids.
25:0 Coenzyme A, also known as pentacosanoyl coenzyme A, is a coenzyme derivative of pentacosanoic acid.
Application
25:0 Coenzyme A or pentacosanoyl Coenzyme A has been used as a substrate for 1-acylglycerol-3-phosphate-O-acyltransferase 11 (AGPAT11) enzyme. It has also been used as an internal standard to quantify fatty acyl CoA extracted from human embryonic kidney 293 cells.
25:0 Coenzyme A has been used as a constituent of the internal standard mixture in liquid chromatography-electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS).
Biochem/physiol Actions
Fatty acyl-CoA plays a vital role in various cellular processes including, energy metabolism, the biosynthesis and recycling of complex lipids, the posttranslational modification of proteins and the regulation of gene expression. In addition, it facilitates most of the fatty acid modification reactions. 25:0 coenzyme A might function as a precursor of sphingolipids. Alterations in the fatty acyl-CoA metabolism leads to obesity, cardiovascular disease, diabetes mellitis and cancer.
Packaging
5 mL Amber Glass Screw Cap Vial (870729P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

UNSPSC Code	12352211
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
InChI key	YJOJYMDYLIGHLQ-SLTOUGITSA-N
SMILES string	O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
assay	>99% (TLC)
form	powder
packaging	pkg of 1 × 5 mg (870729P-5mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 870729P
application(s)	lipidomics
lipid type	coenzymes
shipped in	dry ice
storage temp.	−20°C

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