Merck, 900410C-1MG, 5-PAHSA

Name: 5-PAHSA
Brand: Merck
SKU: 900410C-1MG

Size:1 mg, (O-acyl)-hydroxy fatty acid (OAHFA) 16:0-(5-O-18:0), 5-(palmitoyloxy)octadecanoic acid, chloroform

Catalog Number: 900410C-1MG

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Category

Dry Ice

Pack Size1 mg

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Palmitic acid and hydroxystearic acid (PAHSA) containing (O-acyl)-hydroxy fatty acids are being found in tissues and serum extracts of mouse and human.
Application
5-PAHSA or 5-(palmitoyloxy)octadecanoic acid might be used as (O-acyl)-hydroxy fatty acids (OAHFAs) standard to determine ester position in isomeric OAHFAs by ion trap mass spectrometry. It is also suitable for use as a standard for the quantification of fatty acid esters of hydroxy fatty acids (FAHFAs) by liquid chromatography–mass spectrometry (LC-MS).
Biochem/physiol Actions
Palmitic acid and hydroxystearic acid (PAHSA) levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through G-protein-coupled receptor 120 (GPR120) to enhance insulin-stimulated glucose uptake. PAHSAs are fatty acid esters of hydroxy fatty acids (FAHFAs), which are endogenous lipids with the potential to treat diabetes and inflammation.
Packaging
5 mL Clear Glass Sealed Ampule (900410C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

MDL number	MFCD29905055
UNSPSC Code	12352211
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
InChI key	QBGKCWKQYJQHJX-UHFFFAOYSA-N
SMILES string	CCCCCCCCCCCCCC(OC(CCCCCCCCCCCCCCC)=O)CCCC(O)=O
assay	>99% (TLC)
form	liquid
packaging	pkg of 1 × 1 mL (900410C-1mg)
manufacturer/tradename	Avanti Research™ - A Croda Brand 900410C
concentration	1 mg/mL (900410C-1mg)
lipid type	neutral glyceridesneutral lipids
shipped in	dry ice
storage temp.	−20°C

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