Merck, A5226-25UG, Angiopoietin-1 human

Biochem/physiol Actions
Ang-1 is a ligand with affinity to the Tie-2 receptor tyrosine kinase, which is expressed in early hematopoietic and endothelial cells. Both Ang-1 and Tie-2 play critical roles in embryonic angiogenesis as well as adult vascular integrity.
Ligand with affinity to the Tie-2 receptor tyrosine kinase. Both Ang-1 and Tie-2 play critical roles in embryonic angiogenesis as well as adult vascular integrity.
Physical form
Lyophilized from a 0.2 μm filtered solution in 50 mM Tris and 0.5 M sodium chloride, pH 6.5, containing 50 μg bovine serum albumin per 1 μg of cytokine.
Analysis Note
The biological activity is measured by its ability to inhibit serum deprivation induced apoptosis in HUVE cells.