Merck, LM1302-1EA, 17:0-20:4 PS

General description
In humans, phosphoserine (PS) is present in the intracellular membranes and grey matter. It is localized to the nuclear envelope, endoplasmic reticulum, Golgi apparatus, outer mitochondrial membranes, plasma membranes and myelin.
Application
17:0-20:4 PS or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine has been used as an internal standard:
in lipid extraction from isolated pure mitochondria for mass spectrometry (MS) analysis
for lipid quantification/analysis using liquid chromatography (LC)-MS
for phospholipid quantification by MS
in lysophospholipid acyltransferases (LPLAT) assay
in the preparation of total lipid extracts from lysosome samples by tert-butyl methyl ether (MTBE) lipid extraction protocol for analysis by LC-MS
for ratiometric quantification of phosphatidylserine (PS) using LC-MS

Biochem/physiol Actions
Phosphoserine (PS) maintains the nerve cell membrane and myelin sheath. It is found to be associated with cognitive disability in Alzheimer′s disease.
Packaging
2 mL Amber Glass Sealed Ampule (LM1302-1EA)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Disclaimer
Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.