Merck, LM1906-1EA, 17:0-20:4 PI(3,4,5)P3

Name: 17:0-20:4 PI(3,4,5)P3
Brand: Merck
SKU: LM1906-1EA

Size:1 ea, 1-heptadecanoyl-2-(5Z, 8Z, 11Z, 14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′, 4′, 5′-trisphosphate) (ammonium salt), Avanti Research™ - A Croda Brand LM1906, powder

Catalog Number: LM1906-1EA

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Category

Dry Ice

Pack Size1 ea

TagsChemistry & Biochemicals Biochemicals Avanti Research™A Croda Brand

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Phosphatidylinositol-3,4,5-triphosphate (PI(3,4,5)P3) is localized to the plasma membrane, intracellular sites and the nucleus.
Application
17:0-20:4 PI(3,4,5)P3 or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) has been used:
as a lipid standard in ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS)
as an internal standard in lipid extraction from Drosophila larval tissues
as an internal standard in liquid chromatography tandem mass spectroscopic (LC-MS/MS) analysis of methylated phosphatidylinositol phosphates (PIPs)

Biochem/physiol Actions
Phosphatidylinositol-3,4,5-triphosphate (PI(3,4,5)P3) is involved in protein activation. It is a critical signaling molecule for several cellular processes and acts as a secondary messenger. PI(3,4,5)P3 is also implicated in human pathogenesis.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1906-1EA)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC

Specifications

General

UNSPSC Code	51191904
NACRES	NA.25
Web Name Suffix Override	Avanti Research™ - A Croda Brand
InChI	1S/C46H84O22P4.4H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)64-38(36-62-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2)37-63-72(60,61)68-43-41(49)44(65-69(51,52)53)46(67-71(57,58)59)45(42(43)50)66-70(54,55)56;;;;/h11,13,17,19,21,23,2
InChI key	FSWQCDGXUXSIRI-VHLOILQVSA-N
SMILES string	[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP(O)([O-])=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
form	powder
manufacturer/tradename	Avanti Research™ - A Croda Brand LM1906
packaging	1 ea of 1 × (with stopper and crimp cap (LM1906-1EA))
application(s)	lipidomicsmetabolomics
shipped in	dry ice
storage temp.	−20°C

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