Merck, PHR1909-500MG, Atenolol

Name: Atenolol
Brand: Merck
SKU: PHR1909-500MG

Size:500 mg, Atenolol, (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide, Pharmaceutical Secondary Standard; Certified Reference Material

Catalog Number: PHR1909-500MG

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Category

Certified Reference Materials

Pack Size500 mg

TagsAnalytical Chemistry Reference Materials Certified Reference Materials

CollectionsMerck Certified Reference Materials: CRMs for Calibration, QC & Instrument Validation Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Atenolol is a beta-1 blocker used in the treatment of various cardiovascular diseases.
Application
This pharmaceutical secondary standard can also be used as follows:

Simultaneous analysis of atenolol and nifedipine using magnesium oxide-nanoplatelets (MgO-NPLs) modified screen-printed electrodes (SPEs) by differential pulse voltammetry (DPV) from pharmaceutical dosage forms and urine samples
Voltammetric determination of amlodipine besylate and atenolol in their combined pharmaceutical formulations using a cathodically pretreated-boron doped diamond electrode (CP-BDDE)
Spectrofluorimetric determination of atenolol using gold nanoparticles (AuNPs) based photo probes in commercial tablets
Amperometric estimation of atenolol using bismuth vanadate-bismuth(III) oxide (BiVO₄–Bi₂O) composite electrode in pharmaceutical formulations and human urine samples
Development of a reversed phase-high performance liquid chromatography (RP-HPLC) method coupled to a photodiode array detector (PDA) for the quantitative analysis of atenolol and trimetazidine in human urine and pharmaceutical tablets

Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAC0712 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Specifications

General

UNSPSC Code	41116107
NACRES	NA.24
EC Number	249-451-7
MDL number	MFCD00057645
InChI key	METKIMKYRPQLGS-UHFFFAOYSA-N
InChI	1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
SMILES string	CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
grade	certified reference material
agency	traceable to Ph. Eur. A1340000
API family	atenolol
form	powder
CofA	current certificate can be downloaded
packaging	pkg of 500 mg
application(s)	pharmaceutical
storage temp.	2-30°C
Quality Level	300
Gene Information	human ... ADRB1(153)

Ordering

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