Merck, PHR1941-200MG, Aspirin Impurity E

Name: Aspirin Impurity E
Brand: Merck
SKU: PHR1941-200MG

Size:200 mg, Salsalate, 2-(2-Hydroxybenzoyl)oxybenzoic acid, 2-Hydroxybenzoic acid 2-carboxyphenyl ester, disalicylic acid, salicyloxysalicylic acid, salicylsalicylic acid, Pharmaceutical Secondary Standard; Certified Reference Material

Catalog Number: PHR1941-200MG

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Category

Certified Reference Materials

Pack Size200 mg

TagsAnalytical Chemistry Reference Materials Certified Reference Materials

CollectionsMerck Certified Reference Materials: CRMs for Calibration, QC & Instrument Validation Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
NSAID; Nonacetylated aspirin analog
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB1046 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Specifications

General

UNSPSC Code	41116107
NACRES	NA.24
EC Number	209-027-4
MDL number	MFCD00020252
InChI key	WVYADZUPLLSGPU-UHFFFAOYSA-N
InChI	1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17)
SMILES string	OC(=O)c1ccccc1OC(=O)c2ccccc2O
grade	certified reference material
agency	traceable to USP 1609807
API family	aspirin
CofA	current certificate can be downloaded
packaging	pkg of 200 mg
application(s)	pharmaceutical (small molecule)
format	neat
storage temp.	2-30°C
Quality Level	300

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