Merck, RAB0385-1KT, Atrial Natriuretic Peptide EIA Kit

Name: Atrial Natriuretic Peptide EIA Kit
Brand: Merck
SKU: RAB0385-1KT

Size:1 kit, Natriuretic peptides A, Prepronatriodilatin, ANP, for serum, plasma, culture supernatant and cell lysates

Catalog Number: RAB0385-1KT

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Category

Diagnostic ELISA Kits

TagsProtein Biology Immunoassay Platform Solutions ELISA Kits

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
The ANP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting ANP peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANP-1 targets the common sequence of human, mouse and rat, and thus may be used to detect ANP expression in all these species with high specificity and sensitivity.
Immunogen
Atrial Natriuretic Peptide, synthetic peptide
Application
Atrial Natriuretic Peptide EIA Kit has been used for the quantification of atrial natriuretic peptide (ANP) in cell culture.
For research use only. Not for use in diagnostic procedures.
Atrial Natriuretic Peptide EIA Kit has been used to measure ANP levels in diabetes mellitus patients.
Biochem/physiol Actions
Atrial natriuretic peptide (ANP) is a polypeptide hormone released in response to atrial dilation and it stimulates diuresis, natriuresis and vasorelaxation. ANP acts as an inhibitor of renin-angiotensin-aldosterone system (RAAS) pathway. It also has a major role in body fluid homeostasis and maintenance of blood pressure. Binding of ANP to receptors on target cell stimulate the production of cyclic guanosine monophosphate (GMP). Overexpression of ANP leads to congestive heart failure in the human. Experimental studies show that ANP can be used as a therapeutic for stimulating angiogenesis in ischemic tissues. N-terminal ANP prohormone functions as a biomarker for asymptomatic systolic left ventricular (LV) dysfunction, congestive heart failure and cardiovascular mortality.

Specifications

General

NACRES	NA.32
UNSPSC Code	41116158
species reactivity	mouse, human, rat
packaging	kit of 96 wells (12 strips x 8 wells)
technique(s)	ELISA: suitable
input	sample type serumsample type cell lysatesample type plasmasample type culture supernatant(s)
assay range	inter-assay cv: intra-assay cv: sensitivity: 1.02 pg/mLstandard curve range: 0.1-1000 pg/mL
detection method	colorimetric
shipped in	wet ice
storage temp.	−20°C
Gene Information	human ... NPPA(4878)

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