Merck, SMB00607-1G, Amoxicillin trihydrate: potassium clavulanate (4:1)

Name: Amoxicillin trihydrate: potassium clavulanate (4:1)
Brand: Merck
SKU: SMB00607-1G

Size:1 g, Amoxicillin Trihydrate: Potassium Clavulanate

Catalog Number: SMB00607-1G

Pricing

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Category

Antibiotics & Antimycotics

Pack Size1 g

TagsCell Culture & Analysis Cell Culture Supplements & Reagents Antibiotics

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Amoxicillin trihydrate is a semisynthetic antibiotic, that is used as a medicine.
Application
Amoxicillin trihydrate: potassium clavulanate (4:1) has been used to study its effect on the viral déjà vu disease (neonatal intracerebral (i.c.) infection) in mice model.
Biochem/physiol Actions
Amoxicillin trihydrate is a broad-spectrum, β-lactam antibiotic. It inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. Since amoxicillin is degraded by β-lactamases, it does not show activity against bacteria which produce these enzymes.

Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by β-lactamase enzymes. This increases amoxicillin′s antibacterial activity against bacteria normally resistant to β-lactam antibiotics.
Packaging
1G
Preparation Note
Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.
Material is a powdered mixture of 4 parts amoxicillin trihydrate to 1 part potassium clavulanate.

Specifications

General

NACRES	NA.85
UNSPSC Code	51285005
form	powder
storage condition	(Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.)
color	white to yellow
antibiotic activity spectrum	Gram-negative bacteria
mode of action	cell wall synthesis \| interferes
storage temp.	2-8°C
Quality Level	200

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