Merck, SRP0327-10UG, PADI-2 human

Name: PADI-2 human
Brand: Merck
SKU: SRP0327-10UG

Size:10 μg, Peptidyl arginine deiminase, type II, recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

Catalog Number: SRP0327-10UG

Pricing

Send an RFQ.

View RFQ List

Category

Insect Cell Expression Systems

Pack Size10 µg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Human PADI2, also known as Peptidyl arginine deiminase, type II, (GenBank Accession No. NM_007365), amino acids 1-665 (end) with C-terminal FLAG-tag, MW= 77kDa, expressed in a Baculovirus infected Sf9 cell expression system. Peptidyl arginine deiminase, protein-2 (PADI2) is mapped to human chromosome 1p36. It is expressed in Sertoli cells at the time of testicular development.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. PADI-2 human has been used in in vitro binding assays.
Biochem/physiol Actions
Peptidyl arginine deiminase, protein-2 (PADI2) promotes protein citrullination and represses the multiplication of cells. It helps to transform the amino acid arginine in a protein into amino acid citrulline. PADI2 participates in epigenetic mechanisms. It is linked with rheumatoid arthritis.
Physical form
Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/uL Flag peptide, 3 mMDTT, and 20% Glycerol.

Specifications

General

NACRES	NA.77
UNSPSC Code	12352200
biological source	human
recombinant	expressed in baculovirus infected Sf9 cells
assay	≥60% (SDS-PAGE)
form	aqueous solution
mol wt	77 kDa
packaging	pkg of 10 μg
NCBI accession no.	NM_007365
UniProt accession no.	Q9Y2J8
shipped in	dry ice
storage temp.	−70°C
Gene Information	human ... PADI2(11240)

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.