Merck, Z227323, Supelco® Precolumn Filter

The Supelco Direct-Connect PEEK Precolumn Filter is an in-line HPLC protection component used to trap particulate matter before it reaches an analytical or guard column. Its polyetheretherketone body and cap form a compact housing with a 2 µm stainless steel filter frit. The filter can be connected directly, by hand, to compatible Valco-style column or guard-column end fittings without requiring a separate length of inlet tubing. Intercepting solids from samples, solvent buffers, pump wear or injector seals can help limit column frit blockage, increased backpressure and distorted peak shape. The assembly has a stated maximum pressure of 5,000 psi, a maximum temperature of 100 °C and a 0.015 inch bore. Use a suitable 2 µm element for chromatographic packings of approximately 5 µm or larger, and consider a finer compatible filter for columns with smaller particles where required by the method. Inspect and replace fouled frits when the pressure drop rises, while keeping the filter housing clean during maintenance. The standard supplied filter includes a stainless steel frit and is therefore not entirely metal-free; compatible PEEK replacement frits are separate optional components.