Qiagen, 310107, BioMag Goat Anti-Rat IgG (500 ml)
BioMag goat anti-rat IgG secondary antibody suspension (1 mg/ml)
Catalog Number: 310107
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Category
Pack Size500 mL
| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Recombinant human CXCL1 |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Preparation | The antibody was purified by affinity chromatography. |
| Concentration | 0.5 mg/mL |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C. |
| Application | ICFC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| RRID | AB_3698963 (BioLegend Cat. No. 310107) |
| Structure | Chemokine |
| Distribution | CXCL1 is produced by neutrophils, activated monocytes, fibroblasts, epithelial cells, and endothelial cells |
| Function | CXCL1 chemoattracts neutrophils and induces cell proliferation, tumor angiogenesis, invasion, and metastasis. CXCL1 is induced by LPS, IL-1, TNF, thrombin, and PGE2. |
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| Interaction | Neutrophils and endothelial cells |
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| Ligand/Receptor | CXCR2 |
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| Molecular Family | Cytokines/Chemokines |
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| Antigen References | Anisowicz A, et al. 1987. P. Natl. Acad. Sci. USA 84:7188-92. Caunt M, et al. 2006. Cancer Res. 66:4125-32. Wang D, et al. 2006. J Exp Med. 203:941-51. Datta S, et al. 2010. J Immunol. 184:1484-91. |
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| Gene ID | 2919 |
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| UniProt | View information about CXCL1 on UniProt.org |
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| Clone | A19037I |
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| Regulatory Status | RUO |
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| Other Names | Fibroblast secretory protein (FSP), Growth regulated oncogene 1 (GRO1), Growth regulated oncogene a (GRO a), Growth-regulated alpha protein, melanoma growth stimulating activity (MGSA), MGSA-α, neutrophil activating protein 3 (NAP-3), SCYB1 |
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| Isotype | Mouse IgG2b, κ |
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