Description
Fast, robust and easy library prep with PG-Find software included
Up to 384 adapters for multiplexing on Illumina ® and Element ® sequencing platforms
Detection of whole chromosome aneuploidies and segmental aberrations
Possibility to detect sample swap and external contamination with mtDetect
Updated, streamlined, simple PGT protocol
From DNA to data, the PG-Seq™ Rapid kit v2 includes all reagents required for cell lysis, whole genome amplification, indexing along with the PG-Find™ analysis software for automatic calling of aneuploidy and copy number variants used in PGS (preimplantation genetic screening).
Now you can schedule a one-on-one 30-minute online demonstration with our experts to cover everything you need to know about the PG-Seq™ Rapid protocol and data analysis with PG-Find. Please choose a timeframe that suits you best and we will provide you a Microsoft Teams personal link to join when the time comes. We look forward to speaking with you.
Accurate Copy Number Detection
Extensively tested using over 100 cell lines and genomic DNA samples with known ploidy, including whole chromosome aneuploidies and segmental aberrations as small as 7 Mb. Demonstrated performance with as little as 30 pg of genomic DNA or 5-cell fibroblast samples, representative of a trophectoderm biopsy. See the PG-Seq™ Rapid Kit v2 application note for details.
Flexible Kit Format
The PG-Seq™ Rapid Kit v2 includes 48 reactions. Index sets are available for multiplexing from 48 to 384 samples, with all options available off the shelf. The larger 40 µL WGA PCR 1 reaction volume provides enough template for alternative downstream applications. It also delivers a high yield of 2–4 µg of DNA with just 23 PCR cycles.
Improved whole genome coverage and accuracy
Improved PG-Find quality scores compared to previous kit versions indicate reduced noise and bias, resulting in greater confidence. The PG-Seq™ Rapid v2 WGA PCR 1 product offers comprehensive whole genome coverage, making it compatible with hybridization capture panels.
