Revvity, ES-011-AF, AequoZen Human Adenosine A2α Cell Line, HEK293 Frozen Cells

Name: AequoZen Human Adenosine A2α Cell Line, HEK293 Frozen Cells
Brand: Revvity
SKU: ES-011-AF

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells. Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coe

Catalog Number: ES-011-AF

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Category

Insect Cell Expression Systems

TagsCell Analysis Research & Development Cell Lines & Stem Cells

Description

Frozen Cells validated for calcium testing: Adenosine A2A receptor, human recombinant, in HEK293 host cell. We provide one vial of frozen cells (10 million cells/vial). Some of our Frozen cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information. You are authorized to utilize these frozen cell preparations one time only. Any attempt to transfer, re-use, or propagate these cells is expressly unauthorized and a violation of the product terms and conditions of sale. Features: Pre-validated batches of ready-to-use cells for calcium testing Optimized to alleviate biological variability Step-by-Step protocols for culture-free functional testing on our validated cells Affordable access to small aliquots of cells (minimum size: 10 million cells/vial) Ready-to-use cells for Profiling, Pharmacology or Screening applications Up-scaling and customized developments The AequoScreen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal. The frozen cells approach to functional testing consists in the dissociation of cell culture from testing. That means that we will culture the cells and freeze them with an optimized protocol to stop all replication. These cells are then stored in liquid nitrogen or simply in a -80°C freezer, thawed and used directly in a functional, cellular GPCR test with previously validated performance.

Specifications

General

G-Alpha Coupling Protein	Gα16
G-Alpha Natural Receptor	Gs
Validation	Calcium Luminescence
Application	Drug Discovery & Development
Brand	AequoZen
Host Cell Line	HEK293
Host Species	Human
Product Group	Cell Line
Receptor	Adenosine
Second Messenger Release	Calcium flux
Shipping Conditions	Shipped in Dry Ice
Target Class	GPCR
Therapeutic Area	Cardiovascular Central Nervous System Inflammation Pain
Unit Size	10 million cells

Ordering

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Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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