Revvity, NEV11053, IVISense Annexin-V 750 Fluorescent Probe (Annexin-Vivo)

Annexin A5 (Annexin V) is a cellular protein in the annexin group. Annexin V is a probe commonly used to detect apoptotic cells by its ability to bind to phosphatidylserine, a marker of apoptosis when it is on the outer leaflet of the plasma membrane. IVISense Annexin-V 750 is a targeted fluorescent imaging agent comprising the selective protein, Annexin A5 and a near-infrared (NIR) fluorochrome. IVISense Annexin-V 750 enables in vivo visualization and quantification of the membrane-bound phospholipid, phosphotidylserine, exposed in the outer leaflet of the cell membrane lipid bilayer during the early stages of apoptosis.