Description
MazF is a toxin protein in the toxin-antitoxin module ofE. coli.It possesses endoribonuclease activity and specifically cleaves single-stranded RNA at the 5' end of ACA sequences. This enzyme does not cleave double-stranded RNA, double-stranded DNA or single-stranded DNA. This product, mRNA Interferase-MazF, is supplied as a fusion protein ofE. coli MazF and Trigger Factor (TF) anE. colichaperone protein. The enzyme is also supplied with a 5XMazF buffer (200mM Sodium phosphate, pH 7.5, 0.05% Tween-20).