Description
The EpiXplore Meth-Seq DNA Enrichment Kit is a methylated DNA enrichment and library prep kit. This is a product for separating the methylated and unmethylated fractions of DNA, and generating sequencing-ready Illumina® libraries from sheared genomic DNA. This kit utilizes his-tagged MBD2 protein and CapturemTMNanoprep columns to separate methylated DNA from unmethylated DNA in ~2 hours, and employs our DNA SMARTTMtechnology to generate indexed meth-seq libraries suitable for NGS on Illumina sequencing platforms. Sequencing libraries are generated without the need for enzymatic cleanup or additional adapter ligations. All necessary reagents for producing meth-seq libraries are provided in this kit, including primer sets that contain Illumina index sequences. For more information on the indexes supplied in each kit, please refer to the relevant Certificates of Analysis.