Takara, 635074, Lenti-X™ iDimerize™ Inducible Heterodimer System

The Lenti-X iDimerize Inducible Heterodimer System lets you control the heterodimerization of two different proteins of interest in live cells by adding a small molecule, the membrane-permeant compound A/C Heterodimerizer, to the culture medium. The system includes the Lenti-X iDimerize Inducible Heterodimer Vector Set 1, which contains four lentiviral vectors encoding dimerization tags (DmrA or DmrC, respectively), as well as subcellular localization tags that can be easily fused to your protein of interest. In combination with alentiviral packaging system, the optimized Lenti-X constructs allow for packaging and delivery of high-titer lentivirus to the widest range of cell types. Using this system, the activity and/or localization of the resulting chimeric protein can be controlled by the addition of A/C Heterodimerizer, which is required for heterodimerization and is also included.